Saturday, June 04, 2016 2:50:50 PM
I gave a series of reasons to help explain why Bavi keeps failing in human clinical trials. You avoided addressing my points. Instead you repost nebulous explorations which may include Bavi in some small subset as part of a larger approach to examine combinatorial immunomodulation. By PS targeting, I assume you mean tumor cell receptors like Tims, which associate with PS near their cytoplasmic proximal domains. These are far superior targets as they will be much fewer in number.
As far as what others are testing, why wouldn't they want to explore all aspects when it doesn't cost them money? They are using known effective immunomodulators as the base, not Bavi, then adding various additional factors which they hope will provide synergistic improvement in efficacy, one of a large number of which is Bavi. You are acting as if Bavi is the main driver and component of such studies, and what they consider their best hope. It is very clearly nothing of the sort.
Right, you keep believing that if it gets you through the night. Raw deal in the control arm??? Yes, the nerve of patients in the control arm screwing PPHM by living too long, and the nerve of patients in the control arm screwing PPHM by NOT living longer than those in the control arm.
No, it couldn't be that other companies aren't interested in Bavi, especially after so many failures in clinical trials. It has to be the astute, excellent PPHM management who are protecting the interests of PPHM shareholders by rejecting the plethora of offers made by Big, Medium and small Pharma for Bavi rights.
Pretty arrogant to make that statement after all the Bavi failures. Right, he is an objective observer with no ties to PPHM so his word should be taken as fact.
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