Thursday, July 27, 2006 5:27:51 PM
It is somewhat unfortunate that prospective competition with Vertex is being postured, but it has become a minor issue since Papa Alien started citing Vertex developments a few months back. IMO, demonstrating better success than VRTX for HCV should be viewed as more of an incidental or secondary goal here-- a "windfall" of sorts as Bavi goes through the trial process. The prospect of Bavi replacing interferon and all its nasty side effects as part of standard of care combination treatment seems a better fit with the PPHM business plan, as does the application of Bavi to other viral indications in a way that other drugs are not suited or capable. Can Bavi do the job by itself against HCV? Nice if it can, but it may not need to in order to be viewed as a blockbuster new antiviral drug. There are parallels to Bavi anticancer, as well.
Best wishes and IMO.
KT
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