Monday, May 23, 2016 9:22:14 PM
"IBM CREATES A MOLECULE THAT COULD DESTROY ALL VIRUSES
ONE MACROMOLECULE TO RULE THEM ALL, FROM EBOLA TO ZIKA AND THE FLU
http://www.popsci.com/macromolecule-developed-by-ibm-could-fight-multiple-viruses-at-once
Quote:
For their study, the researchers ignored the viruses’ RNA and DNA, which could be key areas to target, but because they change from virus to virus and also mutate, it’s very difficult to target them successfully.
Instead, the researchers focused on glycoproteins, which sit on the outside of all viruses and attach to cells in the body, allowing the viruses to do their dirty work by infecting cells and making us sick. Using that knowledge, the researchers created a macromolecule, which is basically one giant molecule made of smaller subunits. This macromolecule has key factors that are crucial in fighting viruses. First, it’s able to attract viruses towards itself using electrostatic charges. Once the virus is close, the macromolecule attaches to the virus and makes the virus unable to attach to healthy cells. Then it neutralizes the virus’ acidity levels, which makes it less able to replicate.
As an alternative way to fight, the macromolecule also contains a sugar called mannose. This sugar attaches to healthy immune cells and forces them closer to the virus so that the viral infection can be eradicated more easily.
The researchers tested out this treatment in the lab on a few viruses, including Ebola and dengue, and they found that the molecule did work as they thought it would: According to the paper, the molecules bound to the glycoproteins on the viruses’ surfaces and reduced the number of viruses. Further, the mannose successfully prevented the virus from infecting immune cells."
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