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Monday, 05/23/2016 11:50:28 AM

Monday, May 23, 2016 11:50:28 AM

Post# of 346043
Blaming the control arm for the Sunrise failure is like blaming a victim for the crime. This is sad. Peregrine designed the trial patient selection. Peregrine designed the trial look-in points. Peregrine could have continued the trial despite the IDMC if they wanted. They didn't.

I am not blaming Peregrine for the trial design. Bavi just didn't work as well as we hoped. Simple. Expensive, but simple. Management has to swallow the bitter pill. The question is how to proceed. Sunny assessments of a failed trial get us nowhere.

Sometimes a nail is just a nail. The right tool for a nail is a hammer. Peregrine needs to hammer their cost structure to build a development program reflecting its limited resources or get a partner willing to spend their resources on Bavi-immunotherapy.

Blaming the trial arm is a waste of precious time.

GLTA, Paul



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