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Thursday, 05/19/2016 6:07:17 PM

Thursday, May 19, 2016 6:07:17 PM

Post# of 251948
MRUS (Merus) IPOs 6.33M* shares $10.00 (below expected $14-16 range):

http://www.renaissancecapital.com/news/cancer-therapies-get-a-price-cut:-merus-prices-upsized-ipo-well-below-the-r-39425.html

From F-1/A (https://www.sec.gov/Archives/edgar/data/1651311/000119312516582683/d29248df1a.htm#toc29248_14 ):

We are a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics. Our pipeline of full-length human bispecific antibody candidates, which we refer to as Biclonics, are generated from our technology platform. By binding to two different targets, Biclonics can be designed to simultaneously block receptors that drive tumor cell growth and survival and to mobilize the patient’s immune response by activating various killer cells to eradicate tumors.

In February 2015, we commenced a Phase 1/2 clinical trial of our lead bispecific antibody candidate, MCLA-128, for the treatment of HER2-expressing solid tumors, and we expect to report top-line results from this trial in the second half of 2017. In May 2016, we commenced a Phase 1/2 clinical trial of our second bispecific antibody candidate, MCLA-117, for the treatment of acute myeloid leukemia, or AML. We are also developing MCLA-158, a bispecific antibody candidate that is designed to bind to cancer stem cells expressing leucine-rich repeat-containing G protein-coupled receptor 5, or Lgr5, and epidermal growth factor receptors, or EGFR, for the potential treatment of colorectal cancer, and plan to submit an Investigational New Drug, or IND, application to the U.S. Food and Drug Administration…by the end of 2017 to initiate a Phase 1/2 clinical trial in the United States.

*Assuming exercise of underwriter's option.

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