There is no clinical difference based on primary outcome, that's positive!
The drug is save and no other results were published! Read the primary outcome of shp622 and you would know what Shire was trying to tell!
Things that are equal to the same thing are also equal to one another (Transitive property of equality). If equals are added to equals, then the wholes are equal. If equals are subtracted from equals, then the remainders are equal. Things that coincide wi