Wednesday, May 04, 2016 9:34:17 AM
http://health.usnews.com/health-care/articles/2016-05-03/additional-treatments-offer-little-benefit-for-pancreatic-cancer-study
From the article:
TUESDAY, May 3, 2016 (HealthDay News) -- Additional treatments for locally advanced pancreatic cancer don't appear to boost survival, a new French study reports.
Researchers looked at the effects of adding a second drug -- erlotinib (Tarceva) -- to the initial round of chemotherapy. They also tested whether adding radiation to a second round of chemotherapy (chemoradiotherapy) would offer any survival benefit.
Unfortunately, the addition of the second drug didn't help people live longer, and those on chemoradiotherapy didn't fare any better.
The study was funded by the pharmaceutical company Roche, the maker of Tarceva, and the French National Institute of Cancer.
More than 53,000 Americans are diagnosed with pancreatic cancer annually, the U.S. National Cancer Institute (NCI) says. About 42,000 Americans die each year from the disease, the NCI reports.
The new study focused on 449 people with pancreatic cancer. Their average age was just over 63.
All received standard four-month chemotherapy with the drug gemcitabine (Gemzar). Gemzar is currently used to treat a range of cancers, including pancreatic, ovarian, breast, and non-small cell lung cancers, the drug's labeling information says. For the study, about half the patients (219) also took Tarceva along with Gemzar.
After completing initial treatment, imaging tests revealed that 269 patients appeared to have tumors that were under control. That meant their cancer was stable and didn't appear to have spread, or metastasized.
But the tumors couldn't be surgically removed because they had developed around the arteries surrounding the pancreas, study authors said.
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