Clinuvel Pharmaceuticals (CLVLY)

[FarmaZutical]

Thanks Karin. Yes. The company is very close to treating the first patient after the EMA approval. They have treated more than 100 patients in Switzerland and Italy through special access schemes for a decade but treating patients across Europe at a new higher price will be monumental.

The EMA has put in place some very comprehensive (absurd) safety requirements because they fear off label use. But it seems that everything is now ready to begin actual treatment.

We still don't know the price of the implant. Very soon we will and if it is higher than the market expects the pps will act accordingly.

I believe that EPP - even though only seen as a foot in the door by many - will be a value driver beyond expectations. Patient demand is high. Everything is kept in house. NICE HST is evaluating reimbursement in England meaning that the price for one years treatment exceeds £30.000 GBP / $42.000 USD. £30.000 is the the limit where NICE usually does not reimburse medicines but HST is the scheme for orphan drugs at high costs and low prevalence.

I think we are in for a nice spring. And most importantly: The EPP sufferers are about to receive the treatment they ought to have received years ago. These people's lives are about to change to the better. Dramatically.

GLTA