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Re: To infinity and beyond! post# 143236

Friday, 03/25/2016 11:09:34 PM

Friday, March 25, 2016 11:09:34 PM

Post# of 403217

Seems perhaps the decision makers at Cellceutix have a pretty good idea what they are doing.




"The Psoriasis Area and Severity Index is the most commonly used clinical measure in research, but it has substantial limitations such as low response distribution, no consensus on interpretability, and low responsiveness in mild disease. "

"The main conclusion is that there are no adequately vali- dated clinical measures for psoriasis. As there is no supreme measure, different measures might be ideal for different situations and we might need all of them. When choosing a measure, it is important to determine the most needed features, for example, good responsiveness or sensitivity in mild disease. It may be necessary to combine two or more scores to satisfy all needs. For example, PASI may not be particularly sensitive for mild disease, ..."





http://ac.els-cdn.com/S0022202X15347643/1-s2.0-S0022202X15347643-main.pdf?_tid=cba3dccc-f2fd-11e5-8cfa-00000aab0f01&acdnat=1458960936_0b2a1b1206d027e8b281f6a79c2e2aae


LEGEND OF ABBREVIATIONS
B = Brilacidin, the antibiotic
K = Kevetrin, the oncology drug
P = Prurisol, the psoriasis drug
SAE = Serious Adverse Event
IND = Investigational New Drug


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