Tuesday, March 08, 2016 3:21:33 PM
Oxis is one of the oldest biotech companies in the US, with operations dating back to 1966, and a long history in the antioxidant / anti-inflammatory market.
Oxis specializes in providing kits and reagents for the high-growth cancer and cardiovascular markets, using its strong IP portfolio of over 90 granted or pending U.S. and International patents.
Oxis has a solid, expandable base business in both Research and Clinical Diagnostics products. Over time, Oxis has developed a reputation for superior quality using its services to assist in drug design and development.
Oxis has a well diversified customer base that includes leading research and clinical institutions and stable foreign distributors with years of experience.
Oxis is well positioned to benefit from the need of pharmaceutical and biotechnology companies to outsource assay development due to its current Good Manufacturing Practices (cGMP) and ISO-quality certification. To this goal, Oxis has recently increased its R&D staff in-house and via consulting arrangements.
The Company’s management team and Board of Directors have the necessary experience to take advantage of growth opportuni-ties in therapeutic and nutraceutical marketplaces.
Company Profile
OXIS is a biotech company that develops and commercializes innovative drugs of therapeutic molecules including cannabinoids, which are focused on several cancer indications. Oxis address the clinical shortcomings of existing commercial products in related fields. OXIS has formed relationships with some of the worlds leading cannabinoid researchers and institutions to advance it's technologies.
Oxis International, Inc., through its subsidiary, Oxis Biotech, Inc., discovers, develops, and commercializes therapeutics from its proprietary product platform in various disease areas in the United States. The company is developing drugs for the treatment of cancer and other unmet medical needs. Its lead drug candidates include OXS-2175, a small molecule therapeutic candidate for the treatment of triple-negative breast cancer; and OXS-4235, a small molecule therapeutic candidate to treat multiple myeloma and associated osteolytic lesions. The company was formerly known as DDI Pharmaceuticals, Inc. and changed its name to Oxis International, Inc. in 1994. Oxis International, Inc. was founded in 1965 and is based in Tampa, Florida.
Overview
Treating Non-Hodgkin's lymphoma
OXS-1550 targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When OXS-1550 binds to cancer cells, the cancer cells internalize OXS-1550 and are killed due to the action of drug's cytotoxic payload. OXS-1550 has demonstrated success in early human clinical trials in patients with relapsed/refractory B-cell lymphoma or leukemia.
Treating triple-negative breast cancer
Our lead drug candidate, OXS-2175, is a small molecule therapeutic candidate targeting the treatment of triple-negative breast cancer. In in vitro and in vivo models of TNBC, OXS-2175 demonstrated the ability to inhibit metastasis.
Treating multiple myeloma
Our lead drug candidate, OXS-4235, also a small molecule therapeutic candidate, targets the treatment of multiple myeloma and associated osteolytic lesions. In in vitro and in vivo models of multiple myeloma and osteoporosis, OXS-4235 demonstrated the ability to kill multiple myeloma cells, and decrease osteolytic lesions in bone.
Company Website
http://oxis.com
Corporate Overview - Presentation
Fall 2015
Click the link: http://www.otcmarkets.com/edgar/GetFilingHtml?FilingID=10968247
News, Press, Articles
June 4, 2015
Company Press Release
Oxis Biotech Files U.S. Patent Application Covering p62/Sequestosome 1 Inhibitors For The Treatment Of Multiple Myeloma And Secondary Osteolytic Lesions
June 3, 2015
Company Press Release
Millennium Healthcare Inc. Appoints Anthony Cataldo, CEO of Oxis Biotech, to Board of Advisors
May 12, 2015
Company Press Release
OXIS Biotech Retains The Emmes Group To Assist With Its Strategic Business And Therapeutic Development Initiatives
May 6, 2015
Company Press Release
Oxis Biotech Appoints Cassian Yee, M.D. To Its Scientific Advisory Board
April 14, 2015
Company Press Release
Oxis Biotech Inc. Announces CEO Anthony Cataldo to Participate in Business of Biotech 2015 at the Moffitt Cancer Center
April 1, 2015
Company Press Release
Oxis Biotech Discusses Its Immunotherapeutic Development Strategy
March 31, 2015
Company Press Release
Oxis International Inc. Announces Request for Euronext Trading Suspension
March 30, 2015
Company Press Release
MarijuanaStocks.com to Host Oxis International (OXIS) Conference Call with CEO Tony Cataldo
March 26, 2015
Company Press Release
Oxis Biotech Executes Option Agreement to Certain Patents/Intellectual Properties Owned by the University of Pittsburgh
March 25, 2015
Company Press Release
Oxis Biotech Inc. Announces Corporate Update Conference Call for March 31
March 12, 2015
Company Press Release
Oxis Biotech Licenses Rights To Antibody-Drug Conjugates For The Treatment Of Cancer
February 24, 2015
Company Press Release
OXIS Biotech Issues Letter to Shareholders
February 10, 2015
Company Press Release
Oxis Biotech Inc. Announces Appointment of Dr. Lisa A. Haile to Scientific Advisory Board
February 4, 2015
Company Press Release
Oxis Biotech Inc. Provides Update for P62-ZZ Multiple Myeloma Patent Application
January 29, 2015
Company Press Release
Oxis International, Inc. (OTCQB: OXIS) Announces Approval for Up-Listing to the OTCQB
OXIS on SeekingAlpha Alongside GW Pharma and Insys Therapeutics
This Is Where The Investment Opportunity Is Right Now In Cannabis
January 15, 2015
Company Press Release
Oxis Biotech Inc. Announces Appointment of Dr. James J Mulé to Scientific Advisory Board
January 12, 2015
Company Press Release
Oxis Biotech Executes Worldwide Exclusive Patent Licensing "P62 Chemical Agents and Multiple Myeloma Therapeutics" with Dr. Xiang-Qun (Sean) Xie, Professor of Pharmaceutical Sciences at University of Pittsburgh
Marijuana Stocks.com Article
If You Could Have Bought $GWPH & $INSY at 0.02 Would You?
November 20, 2014
Company Press Release
OXIS International, Inc. announces Changes in Management Team
November 11, 2014
Company Press Release
OXIS International announces Oxis Biotech Inc., Completion of $2.675 million Financing, Appointment of Chief Financial Officer and Board Member
OXIS Conference Call March 31, 2015
CEO Interview with The Wolf of Weedstreet
Management
ANTHONY J. CATALDO
Chairmen and Chief Executive Officer Oxis International, Inc./Oxis Biotech, Inc.
Mr. Cataldo joined the Oxis International Board of Directors in July of 2014. From February 2011 to June 2013 Mr. Cataldo served as FOUNDER and Chairman/CEO of Genesis Biopharma, inc., now known as Lion Biotechnologies, Inc., (LBIO). Mr. Cataldo created the highly successful Lion/Genesis (LBIO) with the inclusion of assets acquired from the National Cancer Institute for the treatment of stage four melanoma. Mr. Cataldo has extensive experience in the biotechnology sector having served as Chairman/CEO of several biotech companies including: MultiCell Technologies, Inc., Calypte Biomedical Corporation, and Senetek, PLC.
STEVEN WELDON
Chief Financial Officer
Mr. Weldon joined the Oxis International, Inc. team as a member of the Board of Directors in September 2014. He was appointed Chief Financial Officer in November 2014. Mr. Weldon was elected President of Oxis International, Inc. November 19, 2014. Mr. Weldon is a certified public accountant licensed to practice in the state of Florida. Mr. Weldon has over 15 years of financial and accounting experience with public and private companies. He most recently was the CFO of Grow BLOX (GBLX) which has made inroads in the newly expanding CANNABIS related field. Steven received his Bachelor of Science degree and his Masters in Business Administration from Florida Southern College, where he was an adjunct professor. Mr. Weldon has years of experience as board member, Chief Financial Officer and Chief Executive Officer of publicly traded companies.
SCIENTIFIC ADVISORY BOARD
XIANG-QUN (SEAN) XIE, M.D., Ph.D., EMBA
Sean Xie, MD, PhD, EMBA is a tenured Professor at the Department of Pharmaceutical Sciences/Drug Discovery Institute at University of Pittsburgh and Associate Dean for Research Innovation at the School of Pharmacy. He is Principal Investigator of an integrated research laboratory of CompuGroup, BioGroup and ChemGroup, and Founding Director of Computational Chemical Genomics Screening Center. Dr. Xie is also Director/PI of NIH funded National Center of Excellence for Computational Drug Abuse Research. Dr. Xie holds joint faculty positions at the Departments of Computational System Biology and Structural Biology, and Pittsburgh Cancer Institute MT/DD Program. He serves as an invited guest editor for AAPS Journal, Editorial Board of American Journal of Molecular Biology, and Associate Editor of BMC Pharmacology and Toxicology. In 2013, he was named an honorary professor of Chinese Academy of Medical Sciences & Peking Union Medical College. Dr. Xie is a recipient of the 2014 American Association of Pharmaceutical Scientists (AAPS) Outstanding Research Achievement Award.
JAMES J. MULE, Ph.D.
Dr. James J. Mule, Ph.D. serves as an Executive Vice President and Associate Center Director for Translational Research, the Michael McGillicuddy Endowed Chair for Melanoma Research and Treatment, and the Co-Director of the Donald A. Adam Comprehensive Melanoma Center at the Moffitt Cancer Center. He then moved to Palo Alto, Calif., where he was involved in the birth of two startup companies while an adjunct faculty member in the Department of Surgery, Stanford University. He moved to Ann Arbor, Mich., as the Director of the Tumor Immunology and Immunotherapy Clinical Research Programat the University of Michigan Comprehensive Cancer Center. Dr. Mule is recognized for his translational research studies in cancer immunotherapy. His research group is involved in vaccine strategies and other approaches to stimulate the immune system to recognize and destroy tumors. The work in these areas has helped to develop new treatments for advanced cancer patients. Dr. Mule serves on the Advisory Boards of seven NCI-designated Cancer Centers and was a member of the NCI’s Board of Scientific and Clinical Counselors. He serves as Chair of the Cellular, Tissue and Gene Therapy Advisory Committee of CBER, FDA, is a Special Government Employee of the NCI and the FDA. Dr. Mule is recognized for his research and clinical contributions to cancer immunotherapy, particularly in solid tumors.
STEPHEN M. CHANG, Ph.D.
Dr. Stephen M. Chang is Vice President-Research & Development at New York Stem Cell Foundation, Chief Scientific Officer at Stemgent, Inc., and Independent Director at MultiCell Technologies, Inc. He is on the Board of Directors at MultiCell Technologies, Inc. Dr. Chang was previously employed as Chief Scientific Officer & Vice President by Canji, Inc., Chief Scientific Officer & Vice President by Schering-Plough Research Institute, and President & Chief Executive Officer by MultiCell Immunotherapeutics, Inc. He also served on the board at Histogen, Inc. He received his undergraduate degree from the University of Michigan and a doctorate degree from the University of California, Irvine.
LISA A. HAILE, Ph.D.
Dr. Haile has special technical experience in molecular biology, immunology, plant biotechnology, including transgenic plants, cell biology, diagnostics, therapeutics, theranostics, virology, drug delivery systems, host-vector systems, high throughput screening and bioinformatics. She has particular experience with patentability, non-infringement and validity opinions; licensing strategies; FDA counseling; due diligence work in connection with venture capital, private and public financing; mergers and acquisitions in the life sciences industry; and strategic counseling for comprehensive life sciences patent portfolio management. Dr. Lisa Haile concentrates on patent protection.
Information on Multiple Myeloma & Cannabidiol (CBD)
After studying the effects of cannabidiol on multiple myeloma cells, researchers found that; “CBD by itself or in synergy with BORT strongly inhibited growth, arrested cell cycle progression and induced MM cells death by regulating the ERK, AKT and NF-?B pathways with major effects in TRPV2+ cells.”
They conclude that; “These data provide a rationale for using CBD to increase the activity of proteasome inhibitors in MM.”
The study, which validates a recent National Institute of Health study which also found that cannabidiol can inhibit cancer cells, was conducted by researchers at the School of Pharmacy at the University of Camerino in Italy.
Stock Information:
Authorized Shares - 600,000,000 a/o Jan 21, 2015
Outstanding Shares - 600,000,000 a/o Apr 23, 2015
Float: 500,863,979 a/o Jan 21, 2015
Market Value - $8,880,000 a/o Oct 23, 2015
Recent GTBP News
- Form 3 - Initial statement of beneficial ownership of securities • Edgar (US Regulatory) • 06/13/2024 08:14:29 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 06/07/2024 09:25:06 PM
- Form SC 13G/A - Statement of acquisition of beneficial ownership by individuals: [Amend] • Edgar (US Regulatory) • 05/24/2024 12:31:08 AM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 05/23/2024 10:04:59 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/23/2024 10:02:41 AM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/15/2024 09:00:40 PM
- Form SC 13G/A - Statement of acquisition of beneficial ownership by individuals: [Amend] • Edgar (US Regulatory) • 02/14/2024 07:46:25 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/01/2024 05:15:12 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 12/21/2023 08:30:39 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 12/04/2023 10:00:11 PM
- Form DEFA14A - Additional definitive proxy soliciting materials and Rule 14(a)(12) material • Edgar (US Regulatory) • 11/06/2023 10:25:12 PM
- Form DEFA14A - Additional definitive proxy soliciting materials and Rule 14(a)(12) material • Edgar (US Regulatory) • 11/06/2023 10:23:32 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 11/06/2023 10:21:33 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/01/2023 01:00:37 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 10/27/2023 09:23:48 PM
- Form SC 13G - Statement of acquisition of beneficial ownership by individuals • Edgar (US Regulatory) • 09/19/2023 03:56:06 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 08/22/2023 08:55:28 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/15/2023 11:29:58 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 08/15/2023 11:26:31 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/07/2023 01:30:27 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 07/05/2023 01:00:11 PM
FEATURED Fifty 1 Labs, Inc. Announces Major Strategic Advancements and Shareholder Updates • Jun 14, 2024 2:07 AM
ECGI Holdings Announces LOI to Acquire Pacific Saddlery to Capitalize on $12.72 Billion Market Potential • ECGI • Jun 13, 2024 9:50 AM
Snakes & Lattes Opens Pop-Up Location at The Wellington Market in Toronto: A New Destination for Fun and Games - Thanks 'The Well', PepsiCo, Indie Pale House & All Sponsors & Partners for Their Commitment & Assistance Throughout The Process • FUNN • Jun 13, 2024 8:18 AM
HealthLynked Introduces Innovative Online Medical Record Request Form Using DocuSign • HLYK • Jun 12, 2024 8:00 AM
Ubiquitech Software Corp (OTC:UBQU) Posts $624,585 Quarterly Revenue - Largest Quarter Since 2018 • UBQU • Jun 11, 2024 10:13 AM
Element79 Gold Corp Files for OTCQB Uplisting, Provides Financial Update • ELEM • Jun 11, 2024 9:25 AM