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Re: DewDiligence post# 855

Tuesday, 07/18/2006 12:25:21 PM

Tuesday, July 18, 2006 12:25:21 PM

Post# of 50406
Dew, Novartis getting into the act would be great, though we haven't seen any evidence of that, yet. They have a ton of money available for acquisitions/partnering though. So far BP interest speculation has centered on - 1) Lilly, who have had an AMPA upregulating program for some time (biarylpropylsulfonamides), and have challenged Cortex's use patent in Europe (twice), and 2) Glaxo, who got into the act several years ago using compounds from NeuroSearch, and who have joined Lilly in the patent challenge in Europe. Other potential players might conceivably be - 3) Amgen (former Neuro head at Lilly jumped over to Amgen several years ago), 4) Pfizer, who previously partnered an unrelated CNS drug with Cortex's partner Servier, and possibly 5) Merck (in an interview several years ago, their neuro head called AMPA upmodulation one of the most promising new neuro platforms). Also, Boehringer Ingelheim has done work with AMPA upmodulators. Then of course there are other players, big and small, who may have a particular interest in ADHD.
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