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Thursday, February 11, 2016 11:04:14 AM
J Am Soc Nephrology Jan issue : Podocyte p53 and experimental Alport Syndrome(podocytes - cells impt function as kidney filters blood-urine)
p53 intact mice had decreased rates of worsening of renal disease. Alport Syndrome genetic disorder of Type IV collagen that causes problems in kidney ear eye, incl high rates of renal failure(as you know ESRD End Stage Renal Disease a big deal for health care- dialysis/transplants)
of course impact in humans not known- just a first mouse study.
But it is interesting and hints at a way forward for K in other diseases
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