Innovation Pharmaceuticals Inc (IPIX)

[To infinity and beyond!]

Antibiotic stewardship and Brilacidin:

It is a good question. Look, Vancomycin presents so many hassles that all of those who prescribe it would rather write an order for another drug. I think Brilacidin should be able to replace it for many reasons already talked about on the board

What will happen if there is a cheap generic alternative Daptomycin, when it goes off patent? How much more attractive will Brilacidin be than such a drug? It depends on what exactly the competition is when Brilacidin becomes available.

One of the most interesting parts of the recent interview with Leo was the discussion about the government holding B in reserve, and not using it. You could really almost hear the conversation leo may or may not have had with the FDA and government officials.

What about a completely new class of drugs? Shouldn't we use the other drugs until we can no longer use them? What is the role of antibiotic stewardship? So far no resistance, but does anyone really belive that no resistance will ever develop? Who knows?

Leo is rehearsing future conversations with the FDA or repeating discussions he has already had, or Jorgensen has had, or whoever their best antibiotic spokesman is.

Brilacidin when it is approved-obv I hope it is a when and not an if- will be a VERY BIG deal, because it is as we all know, a whole new type of antibiotic. I think there will be a lot of discussion as to its proper role, and whether to reserve its use, and I anticipate a real serious conversation about all of these issues