Innovation Pharmaceuticals Inc (IPIX)

[To infinity and beyond!]

So twice a week for a drug with a very short half life?

Is that the optimal dose? Likely not.

Maybe they will simply say we bet K will be safe at 4x week, or safe with a pump, and proceed.

But The risk is obvious if they fail to optimize dosing: toxicity that was not anticipated, or even worse, failure to demonstrate efficacy.

What if they do a phase 2 trial for ovarian that would show efficacy with 4-5 doses/week but no efficacy at 2x week?

That is why I thought they were doing the add on to phase 1- to get the dosing right