Monday, July 14, 2003 11:02:20 AM
Glad to see you got your missing "ger" back!
She is combining her MD and PhD studies. The timescale is a little confusing. Look at this:
"During my first year I developed a rapid method for looking at microsatellite allele frequency differences between populations."
Collins HE, Li H, Inda SE, Anderson J, Laiho K, Tuomilehto J, Seldin MF (2000) A simple and accurate method for determination of microsatellite total allele content differences between DNA pools. Human Genetics, 106:218-226.
I take this to infer that her "first year" (of the PhD work) was 2000. We then see the first paper published March 2002 i.e. this work was done in 2001. When did work on AIMs begin? Well, work on admixture has been going on a long time. This paper is cited a lot:
Chakraborty R, Weiss KM. Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci. Proc Natl Acad Sci U S A. 1988 Dec;85(23):9119-23.
These two papers from 1998 look relevant to me and pre-date the work at Davis:
Parra EJ, Marcini A, Akey J, Martinson J, Batzer MA, Cooper R, Forrester T, Allison DB, Deka R, Ferrell RE, Shriver MD. Estimating African American admixture proportions by use of population-specific alleles. Am J Hum Genet. 1998 Dec;63(6):1839-51.
McKeigue PM. Mapping genes that underlie ethnic differences in disease risk: methods for detecting linkage in admixed populations, by conditioning on parental admixture. Am J Hum Genet. 1998 Jul;63(1):241-51.
What seems to have happened is that Seldin recognized the significance of the AIMs work during 2002. It looks to me as if there has been some communication. I would personally expect some more formal collaboration between Shriver/McKeigue et al and Davis.
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