22nd Century Group Inc (XXII)

[Bubbster]

X-22

I too remember X-22 originally being designed with different levels of nicotine.
But I believe when it was submitted to FDA it was at one low level & was not approved

All I could dig up was this piece from 2011.

The 22nd Century Group is also applying for F.D.A. approval of its own test cigarette, called “X-22,” as a prescription-only smoking cessation device.

“No one has ever sought F.D.A. approval of a cigarette as a medical device,” Joseph Pandolfino, the founder and chief executive of 22nd Century, said in an interview. Preliminary studies show smokers can have an easier time quitting if they taper off the nicotine while still being able to do all the other things they do with cigarettes, he said, but larger studies are needed.