OncoSec Medical Inc (ONCSQ)

[guti]

It is a young company that is growing with no revenue and is at its lowest share price ever, while conducting their most important study.
I would pay more attention to the science and what the future might hold. Here is a recent publication relevant to the science.


Clinical Potential of Electroporation for Gene Therapy and DNA Vaccine Delivery

Published on December 2015 by the NCBI (National Center for Biotechnology Information)

ABSTRACT

Introduction: Electroporation allows efficient delivery of DNA into cells and tissues, thereby improving the expression of therapeutic or immunogenic proteins that are encoded by plasmid DNA. This simple and versatile method holds a great potential and could address unmet medical needs such as the prevention or treatment of many cancers or infectious diseases.
Areas covered: This review explores the electroporation mechanism and the parameters affecting its efficacy. An analysis of past and current clinical trials focused on DNA electroporation is presented. The pathologies addressed, the protocol used, the treatment outcome and the tolerability are highlighted. In addition, several of the possible optimization strategies for improving patient compliance and therapeutic efficacy are discussed such as plasmid design, use of genetic adjuvants for DNA vaccines, choice of appropriate delivery site and electrodes as well as pulse parameters.