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Trade Warning - GALE Unexpected News - http://www.sec.gov/Archives/edgar/data/1390478/000139047815000064/gale-201512228xk.htm Accepted 2015-12-22 16:40:39 On December 16, 2015, Galena Biopharma, Inc. (“Galena”) received a subpoena from the U.S. Attorney’s Office for the District of New Jersey. The subpoena requests the production of a broad range of documents pertaining to marketing and promotional practices related to the product ABSTRAL® (fentanyl) Sublingual Tablets. Galena intends to cooperate with the government’s investigation. Galena can make no assurances as to the time or resources that will need to be devoted to this inquiry or its final outcome, or the impact, if any, of this inquiry or any proceedings on Galena’s business, financial condition, results of operations and cash flows.