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Re: marthambles post# 198185

Friday, 12/11/2015 2:58:49 PM

Friday, December 11, 2015 2:58:49 PM

Post# of 252484
TRVN:

However, TRV027 is unique in that it acutely increases cardiac contractile function, rather than decreasing it - as do angiotensin receptor blockers.



I would disagree with this, and would go so far as to say it's incorrect. TRV027's effect on hemodynamics shows that it works to unload the heart just like ARBs do.

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