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Tuesday, November 17, 2015 8:54:17 AM
"In the pancreatic cancer study, Pan-02 mouse pancreatic tumor cells were orthotopically inoculated (i.e. grafted into its normal place in the body) into immune competent (C57BL/6) mice.Treatment with PRP injected once daily commenced nine days post inoculation, identified as Day 0. At Day 26, significant (p≤0.05) reduction in mean tumor weight was observed, 86% inhibition at the efficacious dose compared to the vehicle control.
In the ovarian cancer study, A2780 human ovarian cancer cells were orthotopically inoculated in female, immune compromised (athymic Nude-Foxn1(NU)) mice. Treatment with PRP injected once daily commenced seven days post inoculation, identified as Day 0. At Day 21, significant (p≤0.05) reduction in mean tumor weight was observed, 54% at the highest efficacious dose identified, and 48% at the lowest efficacious dose. Furthermore, several mice in both treatment groups appear to have no tumor present upon final examination. This is despite identifying tumors in all mice in the experimental control groups.MM's may run this hard! Goning to be fun to watch!
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