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Re: slcimmuno post# 128594

Sunday, 11/01/2015 6:47:50 AM

Sunday, November 01, 2015 6:47:50 AM

Post# of 403159
yes asco 2013 Kevetrin poster shows PARP and PARP 3 cleavage as a target, among others

It is interesting to see how many targets Kevetrin has for cell cycle repair/growth/death, and how many ways it can impact p53.

Thanks for the link to the video. On youtube there is another video that comes up with the one you cited- it shows how PARP is involved with BRCA1 and 2 in some detail. I had never grasped that the BRCA genes were part of the whole repair process, hadn't ever looked at their mechanism in breast cancer despite their fame.

Pretty amazing that Kevetrin is smack dab in the middle of so much action
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