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Re: garydaemon post# 127509

Saturday, 10/24/2015 1:47:22 PM

Saturday, October 24, 2015 1:47:22 PM

Post# of 403593
Looks like Kevetrin is in lead. Nutlins are toxic the company has been searching for years to find an application where thats not true. The other phase1 I have not heard of. The big thing/challenge with reactivating p53 in my view is doing so without toxicity Kevetrin appears to have resounding success here. With signs of efficacy in ovarian, pancreatic and thyroma in phase 1 dose esculation study. I cannot wait to see wait to see what happens in these phase 2 studies with a optimized dosing. Kevetrin clears quickly out of the body increasing dosing frenquency will be interesting!

We also get to see K tackle blood cancers at optimized doses which is likely to occur before the phase 2 solid tumors.