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genisi

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genisi

Re: jellybean post# 196327

Friday, 10/23/2015 3:18:52 PM

Friday, October 23, 2015 3:18:52 PM

Post# of 251888
BLUE/expression of HbAT87Q

Indeed, if one reads the PR it is not clear what and why they have been monitoring along the years but I have been following a bit more closely and they were checking blood Hb concentrations and percentage of each Hb species (by HPLC), of total blood Hb concentrations (in g dl-1). So, the reason for the patient being "low on protein" is not because of waning of transgene expression but more likely related to his endogenous protein.
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