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Re: dr_lowenstein post# 33458

Tuesday, 10/13/2015 7:37:09 PM

Tuesday, October 13, 2015 7:37:09 PM

Post# of 48316
The Patent 9020605, granted to Punit on April 28, 2015 shows that the present invention is directed to an electroporation device comprising an applicator, a plurality of electrodes extending from the applicator, a power supply in electrical communication with the electrodes, and a guide member coupled to the electrodes. It does not mention IL-12 at all, so you are correct.
Such invention is directed to the method of electroporating cells using an electroporation device. However, it has been observed that the higher the impedance, the greater the pain. Therefore, there is a need in the art for an electoporation device that delivers a strong enough pulse for delivering an agent for treatment, but prevents pain due to cell structure impedance. The Punit’s Patent has secured such device with the correct amount of voltage needed, by maintaining the electric field to about 1300 V/cm, which is what Oncosec has already proven in their trials. No other such device can be produced with the same voltage or output.