"orphen drug aproovel is one more piece of confirmation that we have a valid drug." How can you you determine that it's a valid drug before the clinical trials? Sickle Cell Anemia is a genetic mutation that protects the host from malaria. <A HREF="http://sickle.bwh.harvard.edu/malaria_sickle.html" target="_blank">http://sickle.bwh.harvard.edu/malaria_sickle.html</A> You're going to need some serious testing before you can make any claims about cure for SCA.