Avid Bioservices Inc (CDMO)

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Chimeric is affective. This mention is a good explanation




Humanized antibodies are produced by grafting murine hyper variable[disambiguation needed] amino acid domains into human antibodies. This results in a molecule of approximately 95% human origin. However it has been shown in several studies that humanized antibodies bind antigen much more weakly than the parent murine monoclonal antibody, with reported decreases in affinity of up to several hundredfold.