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Re: Echo20 post# 121395

Thursday, 09/10/2015 11:29:35 PM

Thursday, September 10, 2015 11:29:35 PM

Post# of 403754
For Kevetrin phase 2 advanced ovarian cancer it looks the standard care is carboplatin chemotherapy on its own or with another chemotherapy drug called paclitaxel (Taxol). One would have to think this would be one arm of the trial but here is a list of other potentials:

Albumin bound paclitaxel (nab-paclitaxel, Abraxane®)
Altretamine (Hexalen®)
Capecitabine (Xeloda®)
Cyclophosphamide (Cytoxan®)
Etoposide (VP-16)
Gemcitabine (Gemzar®)
Ifosfamide (Ifex®)
Irinotecan (CPT-11, Camptosar®)
Liposomal doxorubicin (Doxil®)
Melphalan
Pemetrexed (Alimta®)
Topotecan
Vinorelbine (Navelbine®)

If I had more time it would interesting to see which are still on-patent and with which companies. Or perhaps an ovarian cancer drug that is still undergoing trials itself used in combination with Kevetrin. Anyways this seems like a situation that might be ripe for a collaboration.

http://www.cancer.org/cancer/ovariancancer/detailedguide/ovarian-cancer-treating-chemotherapy