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Friday, 09/04/2015 8:52:03 AM

Friday, September 04, 2015 8:52:03 AM

Post# of 403077
A bit more science:

ArcherDX- a company based in Boulder with manufacturing facility in, of all places, Beverly MA, has new ways to detect mutations in p53, supposedly easier than prev genetic testing

Also: in Nature, online, more info on p53 mutants as oncogenes. UPenn Med School(first author Zhu) gain of function p53 mutants modify epigenetic enzymes(MLL1, MLL2,MOZ) which then lead to histone methylation and acetylation, which then changes the shape of chromatin to lead to uncontrolled cell replication.

More attempts to clarify the role of p53 in cancer
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