Friday, August 28, 2015 2:08:47 AM
Regarding "accurate" predictions from "inside" sources, when do the sources predict nanomicelle scale-up to be completed and material sent for tox testing?
There is not even a target date being bandied about. They had several target dates but they have long since past and they are now hoping for "sometime in '16."
When and where do the sources predict MERS testing to take place?
PHE has not given them a date. The company believes it was based on PHE being busy with Ebola, but I personally don't agree. PHE stands for Public Health England
How much material will be needed for HerpeCide testing? Will they partner it? Will HerpeCide leap-frog FluCide, since testing takes less material and FDA testing requirements are much less stringent for topical drugs versus IV ones?
They have not met with the FDA nor have they submitted an INDA re: herpecide so they don't have the Tox panel requirements or any other requirements to get IND designation. The Flucide Tox will not be admissible for Herpecide and vice versa. They need to go back to the FDA (or go out of the country) but that is not the plan. They are in discussion to possibly partner, but still have commercial scale production issues to overcome before partners will engage.
Oh, and as far as your supposition as to why ebolacide didn't work, why do you suppose EbolaCide never made it into the endosome to interact with the uncapped Ebola glycoprotein that attaches to the Niemann Pick C1 receptor (and the EbolaCide)...um, is it maybe because of THE SHAPE!
I'm just making all of this up.
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