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Re: cazual post# 1164

Friday, 08/21/2015 8:16:12 AM

Friday, August 21, 2015 8:16:12 AM

Post# of 5907
This is awesome! POSITIVE RESULTS $$$$AVEO$$$$

Results demonstrated that the inhibition of GDF15 function results in the complete reversion of the phenotypic and metabolic changes associated with cancer-related anorexia-cachexia syndrome, or CACS, completely reverting body weight loss and restoring normal body composition of the tumor bearing mice. AV-380 treatment resulted in a catabolic to anabolic metabolic switch and increased food intake, energy expenditure, resting energy expenditure and physical activity. The data highlight the potential of AV-380 as a therapeutic intervention for the treatment for CACS.