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Re: TOB post# 114949

Tuesday, 08/04/2015 5:30:05 PM

Tuesday, August 04, 2015 5:30:05 PM

Post# of 403077
of course what I wrote is sarcastic tripe, warranted by your endless droning about p21. As if it is such a big deal. (Yes I am glad it went up) You write about a complete response of one spleen met? In one patient? And would you hang your hat on that? Without knowing about all the other patients? What about the increase in CEA in that patient?

So we disagree. You would like to attach a lot of significance to p21, when no other helpful info is released by CTIX or Dana Farber.

Nothing about biomarkers such CA19-9 for pancreatic CA or ovarian CA markers, or tumor response for all those other patients. Leo has said that some tumors stabilized in the corporate update, many moons ago, and then....silence

We can draw optimistic conclusions based on clustering of ovarian CA and uterine CA patients and the orphan drug designation, but those are just speculations, and they are worthless.

We still have to sit and wait for real dosing decisions and possible efficacy- on that I am sure we agree.
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