Wednesday, July 29, 2015 9:45:53 PM
Incorrect.
The betabodies patent is US Patent No. 8956616 issued Feb. 17, 2015: Claim 1. A construct comprising an antibody Fc region operatively attached to two .beta.2-glycoprotein I (.beta.2GPI) polypeptides, wherein said .beta.2GPI polypeptides each comprise at least an intact domain V of .beta.2GPI, wherein said intact domain V binds to phosphatidylserine, wherein said .beta.2GPI polypeptides form a dimer when attached to said antibody Fc region and wherein said construct retains the property of binding to phosphatidylserine.
As far as covering all PS targeting agents please refer to US Patent No.6,818,213 issued Nov. 16, 2004:
Claim 1. A binding ligand comprising at least a first targeting agent that binds to an aminophospholipid operatively attached to at least a first therapeutic agent.
I would say that covers all PS targeting agents.
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