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Monday, July 20, 2015 3:49:45 PM
freethemice
Friday, April 06, 2012 11:54:22 AM
Re: cjgaddy post# 78288
Post # of 226979
Here is the poster for AACR 2012 abstract # 1536 on NHS-IL12.
This is the intro and a picture of the structure of the immunocytokine.
Here is the complete poster in jpeg format. You can zoom in to read it.
http://investorshub.advfn.com/uimage/uploads/2012/4/6/drmkzAACR_2012_NHS-IL12_poster.jpg
Thanks to the lead author, Dr. Fallon, at NCI for sending this to me.
It would be very interesting to test this with bavituximab. I think chemo followed by bavituximab, followed by
NHS-IL12 after a short delay. That way the chemo + bavi can attack the tumor first, producing some
necrotic regions, and then the NHS-IL12 can deliver the IL12 to stimulate more immune response to clean up.
In the poster it shows that they tried cyclophosphamide with NHS-IL12 and it improved the response.
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