Tuesday, June 30, 2015 6:01:40 PM
Sequencing of long fragments provides greater insight into genetic variants, enabling a better view of indels and larger structural variants. Partnering this strength of PacBio sequencing with Roche NimbleGen target enrichment enables research breakthroughs through accurate phasing and the identification of haplotypes.
During the webinar, the presenters will:
•Describe a targeted sequencing workflow that combines Roche NimbleGen’s SeqCap EZ enrichment technology with Pacific Biosciences’ SMRT® Sequencing to generate multi-kilobase reads of regions of interest with even coverage.
• Demonstrate that 6 kb fragments can captured, providing sequence information well beyond the targeted capture site and well into (and often across) the adjacent intronic regions.
•Show that multi-kilobase genomic regions can be phased and complex structural variants can be detected, enabling the generation of haplotypes.
http://www.nimblegen.com/news/events/webinar/index.html
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