Innovation Pharmaceuticals Inc (IPIX)

[To infinity and beyond!]

A bit more about abacavir. The hypersensitivity issue(AHR) is exhaustively researched and prob already well discussed on this board elsewhere. Need to screen for HLA-B*57 01 as already said

other side effects(from Up to Date):

Headache 7-13%, nausea 7-19%, depression rash anxiety fevers/chills 5-6%

Boxed warning on very rare lactic acidosis

AHR avoided with the genetic screening and the allele is present in 4-8% Caucasians, 2-3% African americans, less in Asians etc

What I do not know about plaque psoriasis is how great the need is for a new drug. Anybody on the board with bad psoriasis, or know people with it, who can comment? Will ask around. I do not run into dermatologists regularly.

Also , unclear if psoriatic arthritis, a big problem, is treated also with Prurisol, or just the skin manifestations. CTIX site mentions skin only so far as I can tell

George- for RA for example, when I search IL-20 and rheumatoid arthritis, I find little, and it is older data, not so much recent, but I know nothing of this topic