Wednesday, May 20, 2015 9:20:31 AM
Dr. Guenther's case study, titled, "The Search for New Pain Therapeutics with Low Inherent Abuse Potential—A Case for Prodrugs," will be presented on the second day of the ADF Summit, Wednesday, May 20, 2015. The presentation will provide an overview of the successes and failures in the scientific community of finding new pharmaceuticals for the treatment of pain and discuss the potential benefits that prodrugs, such as KP201, may bring to reducing the potential for abuse.
KP201/APAP is KemPharm's most advanced product candidate in development for the treatment of acute moderate to moderately severe pain. Consisting of KP201, KemPharm's NME prodrug of hydrocodone, formulated in combination with acetaminophen, KP201/APAP is designed to deter tampering and abuse.
Dr. Guenther commented, "There is a movement across the country within the pharmaceutical industry and regulatory agencies to combat the epidemic of prescription drug abuse in the U.S., leading to growing demand for better opioid-based medications. We believe that KP201/APAP is at the forefront of this movement, possessing a unique abuse-deterrent chemical structure which ensures that the drug becomes active only when exposed to enzymes in the digestive system. We are pleased to contribute to the refinement of industry best practices for developing abuse-resistant therapeutics."
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