Innovation Pharmaceuticals Inc (IPIX)

[To infinity and beyond!]

Quick follow up to blood pressure discussion. Look at Brilacidin antibiotic fact sheet Feb 2013 put out by Polymedix. There is a discussion of adverse events including a statement that two patients left the study due to increased blood pressure. Those dosing regimens were different than those currently used- specifically, those were multiday and the recent phase 2 was two one day 0.6 and 0.8 as I suspect you all know very well. The one time dosing esp the 0.8 did as well as the 3 day so a once daily dosing is bound to be the future for B.

But it means that Jorgensen mentioned it 1) some patients do get BP increases, and 2)BP increases represented a real problem with the Polymedix phase 2 trial

I once again say that I do not see BP changes as an issue for Brilacidin. We will have phase 3 data to look at some day too.