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Wednesday, April 29, 2015 1:40:10 PM
That is fantastic, BUT we already know that, and will only hear it again at ASCO.
How about the corporate update phrase some pts had stabilization of tumors? What is fanatastic here? 2 of 6 pts at 350/450? 5 of 6, with changes in biomarkers too?
That info we will find out shortly.
How many of the pts even had p53 deletions, where more benefit would be expected? We do not know this either, but will prob learn that also. One expects most of the pts would have such a deletion, or else why not pick another trial.
What about p21- we know it'll go up in later cohorts- they just said so- but we will get this info too. We don't know by how much. I would say the clinical data is more relevant.
My guess is that the ASCO presentation will leave us waiting for the next round of trials with new dosing regimens to get more info.
Continued watchful waiting.
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