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Tuesday, 04/28/2015 11:55:34 AM

Tuesday, April 28, 2015 11:55:34 AM

Post# of 403047
Can you give a drug for an indication that it has not been approved for, is your question? If B approved for cellulitis, how can you give it for pneumonia?

MRSA is MRSA and if you have a great drug then it will be used. There may be more trials for pneumonia treatment, but the data are right there staring at you saying give it.

That is, when it is available.

Vancomycin is really only easy to give in one group of pts- dialysis/renal failure pts. They do not clear the drug so single dose often all that is needed.

Let's look at another classic pt I had yest: she had poor renal function and an ugly knee infection- old and frail. She got a dose of vancomycin 2 days before I saw her and I had to check a Vancomycin level before I knew if she needed another dose, or how much to give.

She has to come back to the ED and sit around for a long time because ED was swamped and then get a Vanco level (took over an hour to get test result....)and then get the drug- very slow to go in to avoid "red man syndrome" bright red flushing of the skin if too fast administration of Vancomycin- a common occurrence. That is a lot of time to lose to get your infection treated. She was here for 7 hours...

yet another candidate for Brilacidin!
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