NanoViricides Inc. (NNVC)

[Doctor_Hari_Seldon]

Some reports have suggested the facility is not fully equipped/operational yet. If so, scale-up activities may not have been investigated too far as of yet. Scale-up is a difficult process at times. I am not sure what sort of exact issues they might be having with it and/or if they are truly serious or not. Even if they had a problem, multiple smaller set-ups could potentially generate enough for final tox and trials.

If they are having an issue with scale-up, I would love to attend a meeting or be the 'fly on the wall'. Not that I could guarantee I could help, but it would be fun to review and think about. Scale-up of a chemical/mechanical process is quite interesting, especially in the fluid mixing and contacting arena. Maintaining equivalent power per unit volumes, torque per unit volumes, vessel geometry ratios, etc., is not always appropriate. Localized shear rates and micro-vorticie dissipation rates may interrupt stable attachment mechanisms. It is both a science and an art to get a handle on. Some might be surprised just how much of a trial and error art it is to produce effective scale-up procedures. Some might also think that in this day and age, these things should be well known, and be surprised to find out just how hands on trial and error it still needs to be.

Wishing all the best of good buys...

HS