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Re: None

Wednesday, 04/01/2015 9:55:25 PM

Wednesday, April 01, 2015 9:55:25 PM

Post# of 403742
update on side issue etc

that is how I see it, side issue. I do not mean to make the proctitis/colitis thing any more than it is, which ain't much(OK, I brought it up)

I sent an email to CTIX and heard back fr Dr James Alexander, from the company

He said that his GI consultants referred to the problem as ulcerative proctitis, and he attached a chapter in a GI textbook as part of his response

NOTA BENE: the first paragraph of his article, sent to me, says that UP is part of UC, not some completely separate issue, but the same medical condition. OK? UP is UC.

For those who wanta quibble about outside inside the colon; look it up: proctitis refers to the rectum, the first six inches of the colon, starting from the bottom. My rectum is inside me, not on the outside, just as yours is. Yes, I know: the therapeutic implications are that you can use topical meds to get at the rectum. I am well aware of steroid treatments etc given from outside, into the rectum, and that may be what CTIX has in mind. But I think of my rectum as inside me, and I am sure that you do too.

So: who cares what they call it, proctitis , or colitis. I would RATHER they use ulcerative colitis- that puts CTIX firmly in the category of potentially having viable therapies for inflammatory bowel diseases such as Crohns and UC and that is a BIG deal. A major deal, if it works.

For those who care to vilify my earlier remarks, get a life. You sound like tribunal lawyers for state trials in the Soviet Union, decades ago.

For those who wish to criticize me directly (or simply converse)I am at samsockwell@gmail.com. I would be glad to hear from you. I am not going to spend the bucks to have private messages. Part of my job every day is bantering back and forth about what is wrong with any given pt, and my job is to make a case that I know what is wrong, or not. I am proven right some of the time, and I am also proven wrong, and that is how it goes. Medicine is not simple.

I bought a lot more shares today, and think the company will do well, even if it takes a while.

Next assignment: I have a long article on MDM2 inhibitors from J Medicinal Chemistry 2014 and will see what it says and report back