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Tuesday, 03/10/2015 7:08:51 PM

Tuesday, March 10, 2015 7:08:51 PM

Post# of 30990
Viagra can have anti-cancer, anti-Alzheimer's disease effects if used with new drugs in News Medical, March 10, 2015

Excerpts:
"Chaperone proteins play an important role in protein folding in human cells and in bacteria and are promising new targets for drugs to treat cancer and Alzheimer's disease and for novel antiviral drugs and antibiotics. How existing drugs such as Viagra or Cialis and a derivative of the drug Celebrex, for example, can reduce the activity of a specific chaperone protein, with the potential for anti-tumor and anti-Alzheimer's disease effects, is described in a Review article in DNA and Cell Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the DNA and Cell Biology website until April 9, 2015."

"The authors describe how OSU-03012, an experimental compound derived from the drug celecoxib (Celebrex) interacts with Viagra or Cialis to reduce levels of chaperone proteins. Reduced levels of HSPA5 and Dna K can interfere with virus replication, promote bacterial cell death, and even make drug-resistant "superbugs" susceptible to existing antibiotics"

Article at:
http://www.news-medical.net/news/20150310/Viagra-can-have-anti-cancer-anti-Alzheimers-disease-effects-if-used-with-new-drugs.aspx

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