Catabasis Pharmaceuticals to Present at Muscular Dystrophy Association Scientific Conference in Business Wire, March 10, 2015
Excerpts: "Catabasis Pharmaceuticals, Inc., a clinical stage drug development company built on a pathway pharmacology technology platform, today announced that CAT-1004 will be featured in an oral presentation and a poster presentation at the upcoming Muscular Dystrophy Association Scientific Conference. The Muscular Dystrophy Association Scientific Conference will be held March 11-14, 2015, in Washington, DC."
"CAT-1004 is a new chemical entity that inhibits activated NF-kB, a protein that coordinates cellular response to muscular damage, stress and inflammation and plays an important role in muscle health. In skeletal muscle, activated NF-kB drives muscle degeneration and suppresses muscle regeneration. In animal models of DMD, CAT-1004 inhibited activated NF-kB, reduced muscle inflammation and degeneration and increased muscle regeneration. In Phase 1 clinical trials, CAT-1004 inhibited NF-kB and was well tolerated with no observed safety concerns. Catabasis Pharmaceuticals plans to initiate a Phase 1/2 clinical trial of CAT-1004 for the treatment of DMD in the first half of 2015."
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