PolyMedix, Inc.(fka PYMXQ)

[Sok]

This is why resistance is unlikely to develop :
“As far as we know, the PolyMedix defensin-mimetics are the only anti-infectives with such a biophysical mechanism of action, directly targeting the membrane, whether bacterial, fungal, or parasitic,” says Dr. Greenbaum. “This makes resistance unlikely to develop. Any biochemical/protein-based mechanism of action is susceptible to resistance via efflux or target mutation.”