Avid Bioservices Inc (CDMO)

[biopharm]

Dmitry Gabrilovich : Peregrine Pharmaceuticals KOL :

Talk: Immunosuppressive mechanisms in myeloid cells (49 min)

http://hstalks.com/main/view_talk.php?t=2956&r=494&j=755&c=252

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ABOUT THIS TALK

Speaker(s)
Prof. Dmitry Gabrilovich Show Biography

Publication Date
December, 2014

Topics Covered
Myeloid derived suppressor cells (MDSC) and their potent immune suppressive activity... more ** see below **

Series
Topical Talks

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**TOPICS COVERED IN THIS TALK


Myeloid derived suppressor cells (MDSC) and their potent immune suppressive activity

MDSC in cancer

MDSC in chronic infections

MDSC during stress

MDSC in surgical trauma


The two main populations of MDSC: monocytic MDSC (M-MDSC) and polymorphonuclear MDSC (PMN-MDSC)

Biological differences between MDSC and their normal counterparts

Multiple mechanisms of expansion regulation and immune suppressive function of MDSC

MDSC role in antigen-specific T cell tolerance in tumor-bearing mice

Therapeutic regulation of MDSC in mice and humans