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Re: None

Monday, 01/12/2015 11:11:03 PM

Monday, January 12, 2015 11:11:03 PM

Post# of 403754
I do hope that the company is willing to enter in to a partnership with Brilacidin ABSSSI sometime after the FDA meeting and before the start of any phase 3. They have a enviable problem in that their pipeline is too deep. A lot of money could be spent developing it all and I am sure financing it will not be a problem for them but it all comes at the price of dilution. Since they are not interested in marketing the drug after approval they might as well share some risk with a partner for a phase 3 and beyond. The initial cash from a partner could fund the company for a few years. Heck, Brilacidin is a powerful, novel antibiotic with 15 years of market rights they could be looking at 100 million or more upfront. I agree with Mr. NR too running a second arm for the 3 day dose seems attractive to me but one would have to see the costs involved. The 3 day would not only act as backup but also you hate to see 98.1% success rate go off the table.

On Kevetrin, I hope they don't turn the phase 1 in to phase 2 efficacy at Harvard. I work at a big university and efficient they are NOT(I cannot emphasis that enough)! I am for finishing up phase 1 at Harvard then go out to a CRO/public hospitals for the phase 2's. Kevetrin appears to be working so get it out of Harvard so it can start saving more lives. If it was me, and I am glad its not, I would walk away Dana Farber p1 results in hand even if they offered to sponsor some or all of the future work. IMO, IMO, IMO