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Re: mcbio post# 185743

Thursday, 01/08/2015 10:19:50 PM

Thursday, January 08, 2015 10:19:50 PM

Post# of 251921
I think it was the NHL data...low ORR of 37% together with safety signals...Grade 3/4 adverse events (>=5%) include thrombocytopenia (37%), neutropenia (22%), anemia (16%), fatigue (12%), leukopenia (10%) and hyponatremia (10%). The most common Grade 1/2 adverse events were: nausea (63%), anorexia (52%), fatigue (46%), and vomiting (36%) that tend to lessen in severity with supportive care and were seen less frequently following cycle 1.

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