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Re: DewDiligence post# 185341

Thursday, 01/01/2015 3:04:35 PM

Thursday, January 01, 2015 3:04:35 PM

Post# of 252785

BMY’s silence regarding plans for its 3-DAA regimen (#msg-108536151) suggests that BMY may not concur with Kolchinski’s “good enough” thesis for late-to-market HCV regimens.



To repeat my tweet response but with more detail... I'd agree BMY might not agree. But Big Pharma often makes misjudgements. E,g, the very common corporate statement "we want to be number 1 or number 2 or divest". So the logic may be sound, but existing big Pharma may not want to engage in this way (this is an example of my initial rebuttal on this thread). They probably need either a TEVA or some smaller company, thinking differently, needs to be willing to take a run at it. And even then, as you point out, it will take some work to figure out what the optimal protocol is.

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