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Friday, December 12, 2014 11:40:54 AM
dr_lowenstein Member Level Friday, 12/05/14 04:06:40 PM
Re: cameron12x post# 27433
Post # of 28063
I saw that and I remain cautiously optimistic but several matters to keep in mind: 1. This is yet another Investigator Sponsored Trial. While these studies can yield important scientific information, they have less weight with FDA. The agency wants sponsored studies. 2. While Merck is supplying drug for the trail, that appears to be the extent of their involvement, so this is not really a big pharma collaboration in the usual sense of the term. 3. If the trail starts in Q1/15 it will be a considerable period of time until completed and results are known.
"This Phase II clinical trial will be conducted as a multicenter Investigator Sponsored Trial (IST), with UCSF and Dr. Alain Algazi as the sponsor. Merck will supply pembrolizumab, and OncoSec will provide electroporation devices and plasmid IL-12. Enrollment is expected to begin in Q1 2015."
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