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alternatepatel

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alternatepatel

Re: eb0783 post# 198146

Monday, 12/01/2014 5:09:40 AM

Monday, December 01, 2014 5:09:40 AM

Post# of 346262
ECYT had 260% higher PFS (statstically significant) than control arm in phase 2 (PRECEDENT trial).

But phase 3 (PROCEED trial) failed due to control arm performing at its best ever.

My point is, there are no guarantees that a 133% pfs/os improvement in p2 with bavi would result in successful p3.

Though improvement at both the doses looks more promising, nothing is a given.
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